41 results
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
autoimmune disease ... (interstitial lung ... disease), PAH ( ... pulmonary arterial ... Scleroderma #SSc #rheumatology
Cutaneous and Systemic Findings in Dermatomyositis
Cutaneous Findings:
 - Heliotrope sign and edema
 - Nail-fold changes
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Cutaneous and Systemic ... - Interstitial lung ... disease - Gastrointestinal ... tract - Cardiac disease ... Dermatomyositis #Diagnosis #Rheumatology
Connective tissue disease-associated interstitial lung diseases

LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
interstitial lung ... SSc: systemic sclerosis ... arthritis SLE : systemic ... Comparison #Table #Pulmonary ... #Rheumatology #
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features of Systemic ... effusion, Restrictive lung ... pain (20%) Renal disease ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Approach to Eosinophilic Lung Diseases
 • Acute Eosinophilic Pneumonia (< 1 wk) - ~30yo, M; Recent
to Eosinophilic Lung ... Diseases • Acute ... , wt loss; CV, CNS ... #Eosinophilic #Lung ... #Diseases #pulmonary
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
highly inflammatory disease ... (CNS) dysfunction ... rash) • Heart, lung ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's Disease ... solid cancers • Systemic ... hepatitis • Pulmonary ... #diagnosis #management ... #treatment #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... of Systemic Lupus ... Cerebrovascular Disease ... #neurology #rheumatology ... cerebritis #diagnosis #management
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
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Systemic Lupus Erythematosus ... Myositis 4% - Lung ... sclerosis, Still's disease ... autoantibodies #signs ... #differential #rheumatology
Management of interstitial lung disease (ILD)-associated with systemic sclerosis (SSc)

Therapeutic indication: absolute decline in FVC >10%
Management of interstitial ... lung disease (ILD ... associated with systemic ... systemicsclerosis #SSc #pulmonary ... #indications #management