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sle erythematosus systemic summary syndrome fungal hematology treatment activation cerebritis coagulation coccidioides coccidioidomycosis comparison dermatology dic disseminated druginduced infections infectiousdiseases
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Cerebrovascular Disease ... autoantibodies that will cause ... #neurology #rheumatology ... #management #treatment
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... Hydroxychloroquine *Short ... #SLE #Summary #diagnosis ... #rheumatology # ... management
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... Positive in 60-80% of cases ... Evolution: Chronic disease ... Erythematosus #Diagnosis ... #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... Non-autoimmune rheumatologic ... and CNS • Headache ... Erythematosus #Diagnosis ... #Rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Discontinuation of causal ... Usual therapeutic management ... Evolution: Chronic disease ... comparison #table #rheumatology ... #diagnosis #management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
• Systemic lupus ... nervous system (CNS ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... nervous system (CNS ... • 8%-27% for CNS ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Thromboembolism (7%) • CNS ... • Severe Liver Disease ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
anterior chest wall, parts ... Rule out other causes ... osteoarticular and skin disease ... SAPHO #Syndrome #Rheumatology ... #diagnosis #management
Coccidioidomycosis (Coccidioides): Valley Fever - Summary Sheet • Morphology • Geography, Reservoir and Mode of Transmission
periods after rain/storms ... tissue, skeleton, CNS ... prostate • Diagnosis ... • Management ... #management #summary
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