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differential neurology erythematosus management sle systemic diplopia myositis signs symptoms syndrome adies autoimmune cauda caudaequina cerebritis comparison complications equina hematology
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
Anti-retrovirals, Gemcitabine Lupus ... uncommon 5-15% of lupus ... myopathy) VA Joint ... #differential #diagnosis ... #comparison #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Aseptic Meningitis, Myelopathy ... autoantibodies that will cause ... permeability Diagnosis ... #neurology #rheumatology
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... Normal CK - Myositis ... femoral heads • Myopathy ... (Also caused by ... signs #symptoms #diagnosis
Important Causes of Diplopia TIER 1-CRITICAL Basilar artery thrombosis, Botulism, Basilar meningitis, Aneurysmn TIER 2-EMERGENT: Vertebral dissection, Myasthenia gravis,
Important Causes ... sclerosis, Thyroid myopathy ... neuropathy, Orbital myositis ... #differential #diagnosis ... #ophthalmology
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
involvement: Intractable nausea ... • Transverse myelitis ... pain • Extra-CNS ... disorders (Systemic lupus ... Manifestations #diagnosis
Differential diagnoses for the neuro-ophthalmologic finding of diplopia. Neoplastic: • Intraorbital meningioma • Pituitary adenoma
Differential diagnoses ... for the neuro-ophthalmologic ... pseudotumor • Orbital myositis ... #Differential #Diagnosis ... #Causes #Ophthalmology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
that results in CNS ... the spinal cord (Myelopathy ... bouts of HTN Diagnostic ... Diagnosis: • ... #diagnosis #management
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
late-onset nemaline myopathy ... Scleromyxedema (CNS ... to cold IgG • Lupus ... Paraproteinemias #Hematology ... #Differential #Diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... Non-autoimmune rheumatologic ... and CNS • Headache ... • Transverse Myelitis ... #Rheumatology
Adie's Pupil What? Unknown nature & benign • Regular and mildly dilated pupil (4-6mm); • Light-near dissociaton;
females Differential Diagnosis ... : • CN Ill Palsy ... dissociation • Other causes ... #Adies #Pupil #PhysicalExam ... #neurology #ophthalmology
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