29 results
differential management autoantibodies erythematosus lupus myopathy neurology signs symptoms systemic antinuclear disease myopathies sle associations autoimmune causes comparison hematology inflammatory
Myositis Specific Antibodies (MSAs) Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ Immune Mediated
Myositis Specific ... Inclusion Body Myositis ... MithuRheum #Myositis ... #rheumatology # ... table
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Autoimmune Myositis ... triad of ILD, myositis ... , and arthritis ... #Autoimmune #Myositis ... #diagnosis #rheumatology
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
• Lupus (SLE): ANA ... others (RNP, aPL antibodies ... Peptide (CCP) • Myositis ... #diagnosis #associations ... #table
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
Other brainstem syndromes ... • Transverse myelitis ... pain • Extra-CNS ... positive NMO only): Myositis ... Manifestations #diagnosis
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
Myositis and Myopathies ... with temporal arteritis ... Inclusion Body Myositis ... , +Anti-dsDNA, Myositis ... BostonChiefs #Myositis
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
Inclusion body myositis ... Pyomyositis, Lyme myositis ... Malignancy-associated myositis ... anti-RNP - (Myositis ... inclusion body myositis
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... SLE), Sjogren's Syndrome ... , Sjögren Syndrome ... , Myositis, Mixed ... #rheumatology #diagnosis
Differential diagnoses for the neuro-ophthalmologic finding of diplopia. Neoplastic: • Intraorbital meningioma • Pituitary adenoma
Differential diagnoses ... • Giant cell arteritis ... Miller-Fisher syndrome ... pseudotumor • Orbital myositis ... Ill and VI palsy
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Manifestations: - Arthritis ... anemia 4% - Myositis ... SLE-Related Auto-Antibodies ... : - ANA 95-100% ... #differential #rheumatology
Inflammatory Myopathies Dermatomyositis • Onset: Subacute • Pattern: Proximal • CK: Up to 50X ULN • Autoantibodies:
Necrotizing Autoimmune Myositis ... Inclusion Body Myositis ... Pattern: Proximal and ... #comparison #rheumatology ... #table
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