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differential management lupus erythematosus systemic antibodies associations comparison disease myositis signs symptoms syndrome treatment ana antinuclear arthritis autoimmune behcet cerebritis
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in ... Rheumatology • ... Lupus (SLE): ANA ... diagnosis #associations ... #table
Inflammatory Myopathies Dermatomyositis • Onset: Subacute • Pattern: Proximal • CK: Up to 50X ULN • Autoantibodies:
Associated Features: Diagnosis ... over years, often diagnosed ... #differential #diagnosis ... #comparison #rheumatology ... #table
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Erythematosus (SLE ... the formation of autoantibodies ... #CNS #neurology ... #rheumatology #
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
Autoantibodies and ... - Drug-induced SLE ... Goodpasture's syndrome #Autoantibodies ... Associations #diseases #diagnosis ... #table #rheumatology
Myositis Specific Antibodies (MSAs) Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ Immune Mediated
Myositis Specific ... TIF1y, NXP2, Mi-2, SAE ... MSAs #clinical #diagnosis ... #rheumatology # ... table
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
anemia 4% - Myositis ... involvement 3% SLE-Related ... Lupusreference #SLE ... #autoantibodies ... #differential #rheumatology
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Highly specific for SLE ... #Antinuclear #autoantibodies ... erythematosus #diagnosis ... #rheumatology # ... table #ANA
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
that results in CNS ... Diagnosis: • ... Evaluate for NMO, SLE ... Disorders: - SLE ... #neurology #differential
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
months) and of autoantibodies ... Erythematosus (SLE ... #comparison #table ... #rheumatology # ... diagnosis #management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
• Anti-Ro/SSA autoantibodies ... Differential Diagnosis ... and CNS • Headache ... • Transverse Myelitis ... #Rheumatology
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