37 results
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
their Disease Associations ... Anti-Scl-70 - Scleroderma ... Autoantibodies #Associations ... #diseases #diagnosis ... #table #rheumatology
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
LAC) • Sjogren Syndrome ... TIF1y, MDA5 • Scleroderma ... #Rheumatology #diagnosis ... #associations # ... table
Hypertension and Altered Mental Status (AMS) - Differential Diagnosis Framework

Hypertension:
 • Hypertensive emergency
 • Hypertensive encephalopathy
Hypertension and ... - Differential Diagnosis ... • Cushing’s syndrome ... /agitation • CNS ... Polyarteritis nodosa • Scleroderma
Clinical Manifestations of Serotonin Syndrome
 • Ophthalmologic: Mydriasis, Ocular clonus (slow horizontal movements)
 • Gastrointestinal: Diarrhea,
Manifestations of Serotonin Syndrome ... Diaphresis, flushing • CNS ... Cardiovascular and ... vital sign abnormalities ... #diagnosis
Signs and Symptoms of Toxidromes

Sympathomimetic / GABAergic withdrawal 
Cholinergic 
Anticholinergic 
Opioid withdrawal 
Neuroleptic malignant syndrome 
Serotonin
Signs and Symptoms ... Neuroleptic malignant syndrome ... Serotonin syndrome ... Toxidromes #Comparison #Table ... Sympathomimetics #Diagnosis
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Asia • HLA-B51 association ... basal ganglia, CNS ... meningitis), MCC CNS ... collaboration • CNS ... #signs #symptoms
Effects of Strokes by Location - Anterior vs Posterior Localization

Anterior Circulation 
 - MCA 
 -
- MCA - ACA ... Artery #Strokes #Syndromes ... Territory #Symptoms #Signs ... Effects #Neurology #Diagnosis ... #Table #Territories
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
: Pathogenesis and ... may be seen in association ... erythematosus (SLE) Signs ... Pathophysiology #Diagnosis ... #Signs #Symptoms
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
searched for when ANA ... SLE-SSc-AlM overlap syndromes ... erythematosus #diagnosis ... #rheumatology #table ... #ANA
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
- Differential Diagnosis ... pulmonary etc) • CNS ... • Acute stroke syndromes ... Lack of UMN/LMN signs ... #Differential #Diagnosis