47 results
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
- Differential ... ITP • SLE • CLL ... Non-lmmune: • HELLP ... Syndrome • TTP ... #Causes #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
coagulation (DIC) - HELLP ... syndrome - ... Hemolytic uremic syndrome ... ) (e.g. lupus, CLL ... #diagnosis #hematology
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Syndrome and Acute ... Pregnancy (AFLP) Three syndromes ... the critically ill ... AFLP #obstetrics #hematology ... #diagnosis #table
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
lymphoproliferative disorder ... Agglutinin Syndrome ... lymphoid malignancy (CLL ... younger pts) Differential ... hemolytic #anemia #hematology
Causes of Thrombocytopenia - Differential Diagnosis Framework
Decreased Production:
 - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
- Differential ... Diagnosis Framework ... antiphospholipid syndrome ... - Pregnancy: HELLP ... #hematology
Differential diagnosis of schistocytes / fragmentation hemolysis:
 • Thrombotic microangiopathies (TMA)
    - TTP
Differential diagnosis ... hemolytic-uremic syndrome ... hemolytic anemia" • HELLP ... syndrome • Catastrophic ... #diagnosis #hematology
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Thrombocytopenia ... Pregnancy Three syndromes ... the critically ill ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison
Elevated Transaminases / Transaminitis - Differential Diagnosis

 • Infectious: HAV, HCV, HEV, EBV, HSV, CMV
 •
breast CA, small cell ... • Congenital: HELLP ... Vascular: Budd-chiari syndrome ... Sinusoidal obstruction syndrome ... #hepatology
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... vonWillebrand #Syndrome ... #Diagnosis #Management ... #treatment #hematology ... #differential
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential ... Diagnosis and Workup ... pylori test (GI symptoms ... not required in all ... #Workup #hematology