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differential management rheumatology causes dermatology hepatology workup cancer classification gastroenterology injury leukemia liver neurology acute anemia chronic erythematosus lactate lupus
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Leukemia #Hematology ... #Oncology #Diagnosis
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
- Differential Diagnosis ... Algorithm Spurious ... disorders • Celiac disease ... Damage: • Post-op surgery ... effect following treatment
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Diagnosis: • ... cells can indicate disease ... microglobulin Treatment ... #workup #oncology ... #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... Allogeneic stem cell ... only curative treatment ... #Management #treatment ... #hematology #oncology
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
ULN R - Renal disease ... diseases, CML, ... plasmacytoma, POEMs syndrome ... Gammopathies #MGUS #diagnosis ... #hematology #oncology
Mucous Membrane Disorder - Differential Diagnosis Algorithm Erosions/Ulcers/Blisters - Primary Dermatologic Diseases •
- Differential Diagnosis ... Algorithm Erosions ... Stevens-Johnson Syndrome ... • Squamous cell ... #Algorithm #causes
Management of Abdominal Distension and Bloating - Treatment Algorithm Definitions Pathophysiology Organic/Pathologic Etiologies: • Small Intestinal Bowel Overgrowth (SIBO)
Intolerance • Celiac Disease ... • Prior GEJ surgery ... Fundoplication, Bariatric surgery ... Irritable Bowel Syndrome ... #Algorithm #Treatment
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
minimal tumor burden Diagnosis ... Waiting" →several RCTs ... chemotherapy for low-risk disease ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Acute Kidney Injury (AKI) in Patients with Cancer Cancer Related • Hypercalcemia • Intravenous contrast •
LC deposition disease ... • Hematologic ... malignancies Treatment ... #AKI #Cancer #Oncology ... #Differential #Diagnosis
Iron Deficiency Anemia - Differential Diagnosis Algorithm Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR • Blood loss:
- Differential Diagnosis ... Algorithm Labs ... Gastrectomy, WHDA syndrome ... Structural: Celiac disease ... #hematology
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