19 results
differential causes hemolytic management oncology workup lupus pancytopenia sle systemic thrombocytosis activation agglutinin approach autoimmune cancer cerebritis chronic cll cns
Warm vs Cold Autoimmune Hemolytic Anemia Warm Autoimmune Hemolytic Anemia: • Mechanism: IgG and Complement-mediated • Etiology:
Warm vs Cold Autoimmune ... Spherocytes • Treatment ... transient hemolysis • Treatment ... Plasmapheresis - VA ... #hematology #diagnosis
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
• Rheumatic disorders ... • Celiac disease ... effect following treatment ... Iron deficiency anemia ... #Hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
- Differential Diagnosis ... Algorithm Blood ... Disease • Marrow ... #Classification ... #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... hemolysis, deficiency anemia ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome ... #Algorithm #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... , Seizure disorders ... Cerebrovascular Disease ... prevention (statin for CVA ... CNS #neurology #rheumatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... ) - HELLP syndrome ... (e.g. primary cold ... lymphoproliferative disorders ... #hematology #anemia
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Algorithm Consumption ... Disorders 1. ... Acquired Aplastic Anemia ... Metastatic Disease ... #Algorithm #Hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
- Differential Diagnosis ... Algorithm Normal ... • Small Bowel Disorder ... Myelodysplastic Syndromes ... #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Algorithm • Sickle ... Agglutination - Cold ... Consider RBC membrane disorder ... #hematology #testing
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Algorithm Consumption ... Disorders 1. ... Acquired Aplastic Anemia ... Metastatic Disease ... #Algorithm #Hematology
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