10 results
Thrombotic Microangiopathies - Primary Thrombotic Microangiopathy (TMA) - Differential Diagnosis Table

 • Thrombotic Thrombocytopenic Purpura (TTP)
Microangiopathy (TMA) - Differential ... Diagnosis Table ... HUS (aHUS) ... Microangiopathy #TMA #hematology ... #differential #
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
Thrombotic Microangiopathy ... - TTP VS HUS ... Often hard to differentiate ... Comparison #Diagnosis #Table ... #Hematology
Pathophysiology of Hypocomplementemic Urticarial Vasculitis

C1q/anti-C1q antibiody ->
Immune Complex Formation - Complement Pathway Activation (C3a and C5a)
Pathophysiology ... Pathway Activation (C3a ... Urticarial #Vasculitis #HUV ... #Pathophysiology ... #Rheumatology
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. 
TTP/HUS indicates thrombotic
TTP/HUS indicates ... thrombotic thrombocytopenic ... thrombocytopenia, Hematology ... #Diagnosis #Differential
Differential diagnosis of schistocytes / fragmentation hemolysis:
 • Thrombotic microangiopathies (TMA)
    - TTP
Differential diagnosis ... hemolysis: • Thrombotic ... known as atypical HUS ... - Drug-induced thrombotic ... #diagnosis #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
syndrome - Thrombotic ... microangiopathy: Thrombotic ... uremic syndrome (HUS ... Extravascular #Causes #differential ... #diagnosis #hematology
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
Glomerulonephritis (RPGN) RPGN has ... three primary pathophysiologic ... Glomerulonephritis #Vasculitis #differential ... diagnosis #algorithm #rheumatology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
blood donor • Pathophysiology ... transfusion • Pathophysiology ... elevated BNP, high CVP ... Transfusion #Reactions #hematology ... diagnosis #comparison #table
D-dimer
Plasma D-dimer is a product of clot breakdown, released upon degradation of polymerized, crosslinked fibrin. Elevated
that coagulation has ... activated, fibrin clot has ... D-dimer has been ... Ddimer #dimer #pathophysiology ... #hematology #differential
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Cell population has ... Neutrophil (Normal) Differential ... #Bandemia #differential ... neutrophil #WBC #CBC #hematology ... #pathophysiology