62 results
MonkeyPox Virus - Summary Review - What we know so far

 • History
 • Epidemiology
 •
Epidemiology • Signs ... Diagnosis • Treatment ... management #virus #infectiousdiseases ... #microbiology #treatment
Leishmaniasis Life Cycle
1) Sandfly takes a blood meal (injects promastigote stage into the skin)
Human Stages:
2) Promastigotes
mononuclear phagocytic cells ... Amastigotes multiply in cells ... and infect other cells ... LifeCycle #diagnosis #pathophysiology ... #infectiousdiseases
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations
Risk Factors:
 - Unclear environmental triggers (may be viral, not
yrs old; F>M Signs ... Anemia - Giant cells ... Temporal #Arteritis #Pathophysiology ... #Diagnosis #Signs
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... organ damage • Treatment ... Lysis Syndrome: • Pathophysiology ... Lysis of tumor cells
Femoral Head Fracture: Pathogenesis and clinical findings
 • Posterior hip dislocation -> Impaction force from femoral
femoral head • Falls ... onto lateral hip Signs ... msk #diagnosis #pathophysiology ... #signs #symptoms
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
mutated in all cells ... Retinoblastoma Signs ... Retinoblastoma #pathophysiology ... ophthalmology #diagnosis #signs
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Reed-Sternberg (RS) Cells ... (LP) tumour B cells ... Responsive to Treatment ... growth, response to treatment ... Classification #pathophysiology
Acute Rheumatic Fever: Pathogenesis and Clinical Findings

Delayed autoimmune reaction
-> Molecular mimicry
-> GAS antigen cross-reacts with host
->
B and CD-4+ T cells ... RheumaticFever #pathophysiology ... #diagnosis #signs
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings
The epidemiology of this disease is 1/340,000 births and roughly double
Signs of immunodeficiency ... maturation of B cells ... from precursor cells ... humoral immunity Signs ... Agammaglobulinemia #XLinked #pathophysiology
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... of UMN and LMN signs ... of UMN and LMN signs ... EMG: LMN Signs in ... diagnosis column Treatment