2778 results
Spectrum of activity for systemic antifungal agents
Antifungals: 5FC, flucytosine; AMB, amphotericin B; ANI, anidulafungin; CAS, caspofungin;
activity for systemic antifungal ... agents Antifungals ... Candida albicans ... .2015.10.012 #Antifungal ... #antibiogram #management
Rare Invasive Yeasts - Species and Antifungal Therapy

Cryptococcus, 
Geotrichum, 
Kodamaea, 
(Pichia)ohmeri, 
Malassezia, 
Pseudozyma, 
Rhodotorula, 
Saccharomyces, 
Saprochaete
- Species and Antifungal ... Trichosporon, Candida ... Invasive #Yeasts #Antifungal ... #Therapy #Management
Invasive Candidiasis (IC)

Diagnosis:
Culture:
 • Gold standard, but Slow (~2-3 days), 50% sensitivity
 • Blood Sample
 •
Tests Conduct antifungal ... Additional management ... Candidiasis #IC #antifungal ... #diagnosis #management ... #candida #auris
Flutycosine - Antibiotics Class Overview
 - 
Mechanism: 5-FC interferes with DNA and protein synthesis.  Only
B for initial management ... meningitis, severe candidal ... for non-severe candida ... #Flutycosine #Antifungal
Candida Glabrata
Species of Candida Most Commonly Isolated in Bloodstream Infections
 • Symptomatic mucosal infection is detected
Candida Glabrata ... unresponsiveness to antifungal ... time to azole antifungals ... candidemia #diagnosis #management ... #fungemia #management
IDSA Recommendations for Treating Mucosal Candidiasis in HIV-AIDS
Oropharyngeal Candidiasis: Initial Episodes (Duration of Therapy: 7–14 days)
Preferred
Note: Systemic antifungals ... #Candidiasis #candida ... Prevention #Treatment #management
Tinea Versicolor (Pityriasis versicolor) 
NOT a dermatophyte infection 
Caused by saprophytic, lipid-dependent yeasts 
Clinical 
 •
meatballs appearance Management ... • Topical antifungals ... • Oral antifungal ... SkinRash #Diagnosis #Management
Antifungal Polyenes - Amphoterecin B, Abelcet, Ambisome - Antibiotics Class Overview

Mechanism: binds ergosterol in membrane and
Antifungal Polyenes ... 2nd-line for candida ... Overview #Polyenes #Antifungal
Antifungal Echinocandins  - Antibiotics Class Overview

Mechanism: Inhibit glucan synthesis in fungal cell wall by blocking
Antifungal Echinocandins ... Cidal vs Candida ... choice for severe Candida ... Echinocandins #Antifungal
Antifungal Coverage Activity Antibiogram 

Spectrum of action of systemic antifungal agents. Solid blocks represent species in
Antifungal Coverage ... action of systemic antifungal ... species in which the antifungal ... PMC3146381/ #Antifungal