10 results
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Growth Hormone (GH ... /Symptoms: • GH ... expansion (e.g. carpal ... #FeedbackLoop #endocrinology ... #pathophysiology
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... GH excess prior ... overgrowth: • Carpal ... signs #symptoms #endocrinology ... #pathophysiology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
paresthesias (carpal ... malignancy Pathophysiology ... pseudo-acromegaly, obesity, hypothyroidism ... Diagnosis #Management #Endocrinology ... #Treatment #Pathophysiology
Tall Stature - Differential Diagnosis Algorithm

Normal Growth (BA=CA)
 • Familial Tall Stature
 • XYY Syndrome
Obese BMI
Puberty Onset • GH ... Excess • Hyperthyroidism ... Precocious Puberty • Adrenal ... • Congenital Adrenal ... Diagnosis #Algorithm #endocrinology
Infographic depicting the main pearls of various types of congenital adrenal hyperplasia for the medical student.
of congenital adrenal ... diagnosis #comparison #treatment ... #Peds #Endocrinology ... #Adrenal #pathophysiology
Short Stature - Differential Diagnosis Algorithm
Normal Variant, Normal Puberty Onset (BA = CA)
 • Familial Short
Cushing's Disease • GH ... Dwarfism) • Hypothyroidism ... • Congenital Adrenal ... Panhypopituitarism Treatment ... Diagnosis #Algorithm #endocrinology
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Endocrine (Hypo/Hyperthyroidism ... Dermatomyositis) AKI - Pathophysiology ... renal ischemia ... oxidative iniury Treatment ... Summary #causes #treatment
Pituitary Mass Effects - Pathogenesis and Clinical Findings
 • Pituitary turnors are almost always a benign
adenomas that require treatment ... following order; GH ... #SideEffects #endocrinology ... mnemonic #GLFTAP #pathophysiology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... Bleeding (64%) • Renal ... variants of both • Acral ... + Bleeding Treatment ... diagnosis #causes #treatment
Adrenal Insufficiency Treatment - Stress Dose Steroids
 • Large Bore IVs, ~2L IVF & Draw workup
Adrenal Insufficiency ... Treatment - Stress ... before concurrent hypothyroidism ... Insufficiency #AI #Treatment ... StressDose #Steroids #endocrinology