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diagnosis lupus signs sle disease erythematosus syndrome treatment video differential druginduced hematology neurology ophthalmology physicalexam stills adies adult adultonset ana
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Diagnosis and Management ... 40, F:M 9:1 • Clinical ... #SLE #lupus #Systemic ... #Summary #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... of Systemic Lupus ... haemolytic Coombs positive ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
Anterior Non-necrotizing Scleritis - Slit Lamp Ocular Examination This 57 yo WM reported to clinic complaining of
Scleritis - Slit Lamp Ocular ... WM reported to clinic ... and had no other symptoms ... which came back positive ... for further systemic
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 Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Constitutional symptoms ... constitutional symptoms ... months to years) Systemic ... comparison #table #rheumatology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
reconstituted immune system ... initiation Clinical ... skin lesions, ocular ... Zoster flare, ocular ... Differential #Diagnosis #Management
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Behçet's Syndrome Systemic ... Skin lesions • Positive ... Syndrome #diagnosis #management ... #signs #symptoms ... #rheumatology #
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... solid cancers • Systemic ... • Ocular: uveitis ... Disease #diagnosis #management ... #treatment #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Positive ANA ≠ Autoimmune ... context of other symptoms ... likely it will be clinically ... • Homogeneous: Systemic ... ANA #patterns #rheumatology
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
Optica (NMO) - Clinical ... desaturation, Scotoma, Ocular ... complications (AQP4-positive ... autoimmune disorders (Systemic ... diagnosis #neurology #symptoms
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Diagnosis = clinical ... Biopsies remain positive ... them, but urgent rheumatology ... Temporal #Signs #Symptoms ... #Diagnosis #Management
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