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diagnosis differential algorithm classification management mcv approach ascorbicacid b12 cirrhosis cobalamin copper dermatology elevatedmcv folate folicacid gastrointestinal hepatology macrocytosis mds
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... • Early Iron ... Deficiency # ... Diagnosis #Algorithm #Causes ... #Hematology
Causes of Iron Deficiency • Diet: ↓ Intake, e.g. vegan, Malnutrition, Polyphenol / tannins, ↓ Vitamin
Causes of Iron Deficiency ... Drugs, H pylori, Celiac ... #Deficiency #Causes ... differential #diagnosis #anemia ... #nutrition
Causes of Iron Deficiency • Inadequate Intake: Vegetarian/vegan diet, Malnutrition • Increased Body Needs: Infants/preschoolers, Pregnancy,
Causes of Iron Deficiency ... Loss (without anaemia ... Bleeding, Edema, Celiac ... IBD, cancer) #Iron ... #nutrition
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... disorders • Celiac ... malignancy • Iron ... deficiency anemia ... Diagnosis #Algorithm #Causes
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased Heme Synthesis or
Causes of Anemia ... Deficiency (Eg ... Causes: Chronic ... Malabsorption, Dietary Deficiency ... #Hematology
Gastrointestinal Causes of Iron Deficiency Anemia • Mass lesions: Carcinoma, Large polyps • Inflammatory: Reflux esophagitis,
Gastrointestinal Causes ... of Iron Deficiency ... Anemia • Mass ... or colon ulcer, Celiac ... #Deficiency #Anemia
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Volume (<80 fL) • Iron ... Chronic Disease Normal ... Diagnosis #Algorithm #Causes ... #Hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
MCH, MCHC, Serum Iron ... RBC Production - Normal ... Deficiency • ... Diagnosis #Algorithm #Causes ... #Hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
Microcytic" • Iron ... deficiency • ... some patients) Normal ... differential #diagnosis #causes ... #hematology
Causes of Copper Deficiency - Differential Diagnosis Hereditary: - Menkes disease, familial hypoceruloplasminemia Decreased / Inadequate Intake:
Causes of Copper ... Deficiency - Differential ... Crohn's disease, Celiac ... , or excessive oral ... supplementation) or iron
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