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diagnosis causes algorithm leukemia cll hodgkins lymphocytic lymphoma management platelets anemia basophilia basophils comparison diffuse fever hemeonc immunecompromised immunocompromised infectiousdiseases
Thrombocytosis - Differential Diagnosis Platelet Count > 450 Reactive: • Anemia/blood loss (Fe deficiency) • Infection/Sepsis • Non-infectious
Thrombocytosis - ... Differential Diagnosis ... Myelofibrosis • Chronic ... #Differential # ... causes #Platelets #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
- Differential ... Myelofibrosis Infectious ... : • Acute or Chronic ... #Differential # ... Algorithm #Causes #Hematology
Isolated Neutropenia - Differential Diagnosis Algorithm Chronic (>3 months): • Extrinsic: Vitamins • Intrinsic: Congenital, Inflammatory Transient: •
Isolated Neutropenia ... - Differential ... Diagnosis Algorithm Chronic ... , Non-infectious ... Diagnosis #Algorithm #hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
- Differential ... ): • Acute infection ... hemorrhage) • Chronic ... #Differential # ... Diagnosis #Causes #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... → Refer to hematology ... : Chronic infections ... #Platelets #Differential ... Diagnosis #Algorithm #hematology
Causes of Isolated Neutropenia - Differential Diagnosis Algorithm Congenital Medications • Anticonvulsants • Antibiotics • Antithyroid • Antihypertensive
Causes of Isolated Neutropenia ... - Differential ... Antineoplastic Viral Infection ... Idiopathic - Chronic ... Algorithm #Causes #Hematology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Pseudotumor - Infectious ... History of Bleeding, Infection ... Age > 50 • Chronic ... Algorithm #Causes #Hematology ... #Oncology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Volume (MCV) - Differential ... Infection) High ... #Anemia #MCV #Classification ... #Differential # ... Algorithm #Causes #Hematology
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
Basophilia - Differential ... allergic reaction or asthma ... Disorders: • Chronic ... ’s Disease • Asthma ... Diagnosis #causes #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Malaise, bleeding, infections ... basophilia, and thrombocytosis ... or functional neutropenia ... #Leukemia #Hematology ... #Oncology #Diagnosis
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