13 results
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
Basophilia - Differential ... Myeloproliferative Disorders ... : • Chronic myeloid ... #Differential # ... Diagnosis #causes #hematology
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
- Markers and Differential ... - CD7, CD3 Chronic ... • Lymphoid (CLL ... #hematology #Markers ... #Differential #
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
- Differential ... ): • Acute infection ... inflammatory disorders ... myeloid leukemia (CML ... Diagnosis #Causes #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
- Differential ... Myelofibrosis Infectious ... • Rheumatic disorders ... #Differential # ... Algorithm #Causes #Hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Malaise, bleeding, infections ... eosinophilia, basophilia ... , and thrombocytosis ... or functional neutropenia ... #Leukemia #Hematology
Causes of Splenomegaly - Differential Diagnosis Algorithm
Infectious
 • Bacterial
 • Viral (EBV)
 • Parasitic
 • Fungal
Congestive
Diagnosis Algorithm Infectious ... Myeloproliferative disorders ... vera, essential thrombocytosis ... Disease • Sickle Cell ... Algorithm #Causes #Hematology
Causes of Neutropenia - Differential Diagnosis
Neonate:
 - Infection - by far the most common cause
 -
- Differential ... Diagnosis Neonate: - Infection ... including white blood cell ... #differential # ... diagnosis #causes #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... weeks without infection ... lymphoproliferative disorders ... Cytopenias: • Neutropenia ... workup #oncology #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Chronic Lymphocytic ... leukemia in adults • Disorder ... Complications: 1) Infection ... PRCA, autoimmune neutropenia ... Leukemia #oncology #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Consider sickle cell ... thalassemia, S Lepore • Basophilic ... inclusions - If infection ... Consider RBC membrane disorder ... Algorithm #workup #hematology