10 results
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
Causes of Extravascular ... and Intravascular ... Diagnosis Algorithm ... Extravascular ... #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Intravascular vs ... Extravascular Causes ... Intravascular ... #Hemolytic #Intravascular ... #hematology #anemia
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table

Warm AIHA (48-70%)
Cold AHA (16-32%)
 • Donath-Landsteiner HA (paroxysmal
Autoimmune Hemolytic ... Table Warm AIHA ... #Hemolytic #Anemia ... #Diagnosis #Table ... #hematology
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
Hemolytic Anemias ... of anemia and hemolysis ... Hemolytic Anemias ... (AIHAs) • Alloimmune ... #Algorithm #hematology
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 • Enzyme deficiencies ex. G6PD, pyruvate kinase 
 • Hemoglobinopathies
for Hemolytic Anemia ... IVIG infusion Intravascular ... Causes: • MAHA ... udaygulati #Hemolytic ... classification #hematology
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
microangiopathic hemolytic ... Microangiopathic hemolytic ... as disseminated intravascular ... microangiopathic #hemolytic ... #anemia #Hematology
Iron Deficiency Anemia - Differential Diagnosis Algorithm

Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR

 • Blood loss:
Algorithm Labs ... • Iron loss: Intravascular ... (not extravascular ... ) hemolysis, Intensive ... #hematology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Fragmentation - MAHA ... Membrane): - Autoimmune ... Urobilinogen #Hemolysis ... #hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
-100): • Non-hemolytic ... anemia, CKD • Hemolytic ... - Extrinsic: Autoimmune ... , MAHA, Macroangiopathic ... #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Diagnosis: • hemolytic ... • Compensated hemolysis ... the RBCs causing intravascular ... hemolysis on rewarming ... #anemia #hematology