564 results
Immune-related adverse events (irAE) of  immune checkpoint inhibitors (ICI) 

- By Antoine Briantais 
Dr. Benjamin
checkpoint inhibitors (ICI ... TerrierBen #irAE #ICI ... #CheckpointInhibitors
Intracranial Hemorrhage (ICH) and Increased Intracranial Pressure (ICP) - Pathophysiology
ICH Management:
1. Manage Blood Pressure
  •
Pathophysiology ICH ... • Spontaneous ICH ... blood volume and ICP ... if needed ICP ... High ICP: 20.
Decubitus Ulcer - Diagram of stages. A, Stage I pressure ulcer. B, Stage II pressure ulcer.
B, Stage II pressure ... C, Stage III pressure ... Ulcers #Stages #III
Antiarrhythmics - Vaughan Williams Classification
Class I (Ia, Ib, Ic) - Na+ Channel Blockade
 • Slows depolarization
Class I (Ia, Ib, Ic ... complex Class II ... interval Class III
Antiarrhythmic Drug Classes 
IA: "Police Department Questions 
IB: Liquored Man 
IC: For Peeing, 
Ill: After Drinking
Liquored Man IC ... Lidocaine Mexiletine IC ... Propafenone III
Unicondylar proximal phalangeal fractures can be classified into four basic groups: oblique volar (I), long sagittal
long sagittal (II ... dorsal coronal(III
Capnography
Measurement of exhaled carbon dioxide can be used to confirm ETT placement, for safer procedural sedation,
Downsloping phase III ... Prolonged phase II ... /III: bronchospasm ... Dimorphic phase II ... /III: right mainstem
Important Blood Pressure Targets in the ED
Subarachnoid Hemorrhage: 
    SBP < 140 -
raised ICP: MAP ... 80 Spontaneous ICH ... raised ICP: MAP ... raised ICP: MAP
Approach to ECGs
Check
 - Age, gender, name
 - 25mm/s; 10mm/mV
 - 1mm = 40ms; 0.1 mV
Rate
(2) P+ve in l, II ... QRS +ve in I, II ... V-pacemaker, ↑K, ICD ... congenital, MI, high ICP
Check point inhibitors and Side Effects - Immune-related adverse events (IRAEs)

What are the side effects?
 -
immunosuppresion #CheckPointInhibitors