23 results
rheumatology management differential autoantibodies erythematosus leukemia lupus systemic anemia antinuclear associations autoimmune chronic clinical cll lymphocytic myopathy sle vasculitis agglutinin
Myositis Specific Antibodies (MSAs) Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ Immune Mediated
Antibodies (MSAs ... Anti-Synthetase Syndrome ... MSAs #clinical #diagnosis ... #rheumatology # ... table
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
• Lupus (SLE): ANA ... others (RNP, aPL antibodies ... Peptide (CCP) • Myositis ... #diagnosis #associations ... #table
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Autoimmune Myositis ... less systemic symptoms ... anti-synthetase syndrome ... /full triad at diagnosis ... #diagnosis #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... SLE), Sjogren's Syndrome ... Arthritis, Sjögren Syndrome ... , Myositis, Mixed ... #rheumatology #diagnosis
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
Disease Associations ANA ... La) - Sjogren's syndrome ... Associations #diseases #diagnosis ... #table #rheumatology ... #antibodies
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
anemia 4% - Myositis ... SLE-Related Auto-Antibodies ... : - ANA 95-100% ... autoantibodies #signs #symptoms ... #differential #rheumatology
Statin Induced Muscle Toxicity - Summary Clinical Presentation: • Elevations of serum creatine kinase with proximal myalgia
• Myalgia • Myositis ... inclusion body myositis ... myopathy (IMNM) → Antibodies ... Atorvastatin Diagnosis ... toxicity #myopathy #diagnosis
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Sensitive Antibodies ... Donath-Landsteiner Antibodies ... Cold Agglutinin Syndrome ... Donath-Landsteiner (IgG) antibodies ... hemolytic #anemia #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
minimal tumor burden Diagnosis ... lymphadenopathy and ... 3) Monoclonal antibodies ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Symptoms: - Fever ... development of skin symptoms ... , breast CA - Hematologic ... #diagnosis #dermatology ... #oncology
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