13 results
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Diagnosis Algorithm ... Chemotherapy) ... Non-lmmune: • HELLP Syndrome ... #Diagnosis #Algorithm ... #Causes #Hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation ... ATRA treatment Pathophysiology ... myalgias, HoTN, edema ... : >3 symptoms, or ... initiation • Differential
Disorders of Pigmentations - Hypopigmentation and Hyperpigmentation - Differential Diagnosis Algorithm

HYPOPIGMENTATION
Diffuse Congenital - Generalized hypopigmentation of
Diagnosis Algorithm ... • Tanning • Adverse ... McCune Albright syndrome ... Diagnosis #Algorithm ... #causes
Restrictive Cardiomyopathy - Diagnosis and Causes
Clinical: Dyspnea, Exercise Intolerance, ↑ "Right Sided-Symptoms" (ascites, hepatomegaly, ↑↑peripheral edema)
Physical
↑ "Right Sided-Symptoms ... , ↑↑peripheral edema ... Hyper-eosinophilc Syndrome ... #Causes #differential ... #cardiology #algorithm
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
Definition: • Severe adverse ... • Facial Edema ... Resolution > 15 days Differentials ... SinaiBmoreIMRes #DRESS #Syndrome ... #dermatology #diagnosis
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... : • Pathophysiology ... - Cytotoxic chemotherapy ... #TLS #diagnosis
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm

DIFFUSE
Scarring - Irreversible-biopsy required
 • Lupus
Diagnosis Algorithm ... Effluvium • Chemotherapy ... • Loose anagen syndrome ... Diagnosis #Algorithm ... #causes
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
disease, Cancer chemotherapy ... Etiology: • Pathophysiology ... Neurological symptoms ... Reversible course Differential ... the underlying cause
Skin Hyperpigmentation - Differential Diagnosis Algorithm
Diffuse:
 • Tanning
 • Adverse cutaneous drug eruption
 • Addison's disease
Diagnosis Algorithm ... • Tanning • Adverse ... McCune Albright syndrome ... Diagnosis #Algorithm ... #causes
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
Diagnosis Framework ... Non-compressive Spinal Cord Causes ... Metabolic: - Chemotherapy ... MCTD, Sjogren syndrome ... #algorithm