473 results
diagnosis differential causes algorithm hematology management clinical pathophysiology signs symptoms oncology pharmacology workup neurology cardiology nephrology hemolytic mnemonic treatment deficiency
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm Sequestration: • Splenomegaly Marrow Infiltration: • Hematologic and non-hematologic
suppression: • Chemotherapy ... Toxins • Aplastic Anemia
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
particular degree of anemia ... Index < 2: • Anemia ... failure: Aplastic anemia ... suppression (e.g. drugs, chemotherapy ... Hospital-acquired anemia
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Iron deficiency anemia ... Disease, MDS, Chemotherapy ... iron deficiency anemia ... Autoimmune hemolytic anemia ... autoimmune hemolytic anemia
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Megakaryopoiesis • Aplastic Anemia ... Chemotherapy)
Causes of Iron Deficiency • Diet: ↓ Intake, e.g. vegan, Malnutrition, Polyphenol / tannins, ↓ Vitamin
Children, EPO / chemotherapy ... differential #diagnosis #anemia
Dyspnea - Considerations with Malignancy Directly Malignancy Related: - Lymphangitic spread to lung - Malignant pleural effusion
Treatment Related: - Chemotherapy ... - Cytopenias (anemia
FAT RBC Mnemonic for Causes of Macrocytic Anemia (MCV > 100) F - Folate (Fetus) and B12 Deficiency
of Macrocytic Anemia ... a response to anemia ... Chemicals (drugs, chemotherapy ... Causes #Macrocytic #Anemia
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... Immune Aplastic Anemia ... as in Fanconi anemia ... Cytotoxic drugs/Chemotherapy
Hyperuricemia - Differential Diagnosis Algorithm Primary - Over-production • Increased turnover of nucleotides Primary
- Hemolytic Anemia ... Psoriasis • Chemotherapy
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
• Hemolytic Anemias ... Microangiopathic hemolytic anemia ... - Pernicious anemia ... Drugs (alcohol, chemotherapy
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