20 results
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
Basophilia - Differential ... Influenza • Chickenpox ... Other Causes ... Differential #Diagnosis #causes ... #hematology #basophils
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus
Clinical and Immunologic Criteria

CLINICAL CRITERIA
 - ACUTE CUTANEOUS LUPUS
SLE Diagnostic Criteria ... Erythematosus Clinical and Immunologic ... CRITERIA - ACUTE ... <100,000/MM3) IMMUNOLOGIC ... #Diagnosis #Rheumatology
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased Heme Synthesis or
Causes of Anemia ... Deficiency (Eg Causes ... MCV/RBC<13, +/- basophilic ... Diagnosis #Algorithm #Causes ... #Hematology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
Classification Criteria ... lupus nephritis Immunologic ... Classification #Criteria ... Erythematosus #diagnosis #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Cytopenia: Common • Immunologic ... Positive in 60-80% of cases ... Management #Summary #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
10% of all lupus cases ... drug-dependent) • Immunologic ... Discontinuation of causal ... Cytopenia: Common • Immunologic ... comparison #table #rheumatology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
transfusion • Criteria ... : ARDS Berlin Criteria ... without other cause ... transfusion • Criteria ... Transfusion #Reactions #hematology
The algorithm below shows how pre-test probability could be combined with various criteria to determine which
combined with various criteria ... negative Reller Criteria ... negative Bouza Criteria ... HSV PCR would cause ... chemistries and immunologic
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
DDX - Other causes ... hypogammaglobulinemia #immunology ... #hematology #diagnosis
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
positive in 90% of IE cases ... • Petechiae Immunologic ... Septic Emboli Cause ... -> TEE • Duke Criteria ... Treat underlying cause