15 results
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
Differential Diagnosis Algorithm ... Pseudo Pelger-Huet, Macrocytic ... anemia - ... • Lymphoid (CLL ... #hematology #Markers
Anemia Diagnostic Algorithm

Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... 95 (or 100) is macrocytic ... acute blood loss, hemolysis ... (BM) ablative disorders ... #Workup #Hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
Differential Diagnosis Algorithm ... Hypersplenism • Secondary ... Polychromatic Macrocytes ... Bleed • Hemolysis ... #Causes #Hematology
Hyperuricemia - Differential Diagnosis Algorithm
Primary - Over-production
     • Increased turnover of nucleotides
Primary
Differential Diagnosis Algorithm ... • Starvation Secondary ... Lymphoproliferative Disorders ... (CML) - Hemolytic ... Anemia - Others
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
RBC) Morphology Microcytic ... (sometimes) Macrocytic ... Microangiopathic Hemolytic ... Unstable hemoglobin disorders ... differential #diagnosis #hematology
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
malignancies • Anemia ... iron deficiency, hemolysis ... Chronic inflammatory disorders ... Chronic myeloid leukemia ... (CML) - Dr.
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
AIHA Primary Secondary ... Secondary Cold ... • Symptoms of anemia ... anemia • Cold ... #anemia #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Differential Diagnosis Algorithm ... Consider sickle cell ... Consider RBC membrane disorder ... #workup #hematology
Causes of Splenomegaly - Differential Diagnosis Algorithm
Infectious
 • Bacterial
 • Viral (EBV)
 • Parasitic
 • Fungal
Congestive
• Lymphoma • Leukemia ... Myeloproliferative disorders ... Serum Sickness Hemolytic ... Disease • Sickle Cell ... #Causes #Hematology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Tests/Enzymes: • Cholestatic ... renal failure/uremia ... • Lymphoma • Leukemia ... Pruritus #primary #secondary ... #generalized #dermatology