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causes algorithm anemia platelet workup leukemia management atlas bleeding chronic cll disease lymphocytic morphology purpura rash rbc secondary thrombocytosis agglutinin
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. TTP/HUS indicates thrombotic
for workup of thrombocytopenia ... purpura/hemolytic ... , Hematology 2012 ... , p 193 #Diagnosis ... #Differential #
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
of Bleeding / Bruising ... - Differential ... Diagnosis Algorithm ... Thrombocytopenia ... #Causes #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... microangiopathy: Thrombotic thrombocytopenic ... lymphoproliferative disorders ... Extravascular #Causes #differential ... #diagnosis #hematology
Thrombocytopenia - Differential Diagnosis Algorithm Decreased production: • Bone marrow suppression • Bone marrow failure • Bone
Thrombocytopenia ... - Differential ... Diagnosis Algorithm ... Connective tissue disorders ... #hematology #platelets
Von Willebrand Disease - Most common inherited bleeding disorder Clinical • Easy bruising •
inherited bleeding disorder ... Clinical • Easy bruising ... platelet count (mild thrombocytopenia ... VonWillebrand #Disease #Diagnosis ... #Hematology
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
Diagnosis Algorithm ... Congestive • Cirrhosis ... Myeloproliferative disorders ... Serum Sickness Hemolytic ... #Causes #Hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Diagnosis Framework ... DIC/TTP/HUS - Hemolytic ... #Diagnosis #hematology ... #nonpalpable #dermatology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Thrombocytosis - Differential ... Diagnosis Algorithm ... • Rheumatic disorders ... following EtOH induced thrombocytopenia ... #Causes #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential ... Diagnosis Algorithm ... Schistocytes, thrombocytopenia ... Consider RBC membrane disorder ... #workup #hematology
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
Purpura or Easy Bruising ... Non-immune - Haemolytic ... bypass Vascular disorders ... #Causes #peds #pediatrics ... #diagnosis #differential
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