20 results
Lupus Nephritis Primer
Class I - Minimal Mesangial
Class II - Mesangial Proliferative
Class Ill - Focal Proliferative
Class IV
Nephritis Primer Class ... Proliferative Class ... IV - Diffuse Proliferative ... Lupus #Nephritis #SLE ... differential #diagnosis #management
Management of Lupus Nephritis
Lupus nephritis (LN) in 10 to 40% of SLE
Hallmark = proteinuria 20.5 g/g
in 10 to 40% of SLE ... Classification: • Class ... mesangial LN • Class ... proliferative LN • Class ... Membranous LN • Class
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Causes of Diffuse ... Differential Diagnosis Algorithm ... Reactive: - Systemic ... Inflammatory • Systemic ... #Causes #Hematology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
pericarditis • Hematologic ... > 0.5 g/24 hr, Class ... lupus nephritis, Class ... Classification #Criteria #SLE ... #Systemic #Lupus
Bronchiectasis: diagnosis and management 

Causes of localized -> diffuse bronchiectasis
Foreign body, Bronchial stenosis (tumor, .. ),
diagnosis and management ... Causes of localized ... -> diffuse bronchiectasis ... RA, Sjögren, SLE ... Differential #workup #algorithm
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... and Management ... Positive in 60-80% of cases ... #lupus #Systemic ... #Summary #rheumatology
Algorithm for the Treatment of Membranous Lupus Nephritis
Sub-nephrotic-range proteinuria (<3.5g/d, normal serum albumin) and Preserved kidney
Algorithm for the ... treat non-renal SLE ... immunosuppression to treat class ... therapy to treat class ... #Treatment #management
DPP4 Inhibitors - Normal and Renal Dosing

Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
about this drug class ... If you see a patient ... on a lower dose ... This drug class ... #Pharmacology #Management
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Disorders secondary to Systemic ... Abnormality • SLE ... #Secondary #dermatology ... Differential #Diagnosis #Algorithm ... #causes
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
site in lymphatic system ... with lymphatic system ... are present • Classic ... lymphadenopathy more diffuse ... pathophysiology #Hematology