14 results
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing

Renal Dosing:
Apixaban (25% renal clearance):
DOAC: Cheat Sheet ... VTE and Renal Dosing ... Renal Dosing ... Apixaban (25% renal clearance ... @Bloodman #DOAC
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
Management of DOACs ... recent creatinine clearance ... (calculated using ... Discontinuation of Therapy ... Resumption of Therapy
Heparin, Fondaparinux, and Novel Oral Anticoagulants - Pathophysiology

Anticoagulation with parenteral (intravenous or subcutaneous) and oral anticoagulants
Anticoagulants - Pathophysiology ... mainstay of VTE therapy ... #Pharmacology #Pathophysiology ... Heparins #LMWH #UFH #DOAC ... #Fondaparinux #NOAC
Renal Replacement Therapy (RRT) - ICU One Pager Summary
Indications (AIEOU):
 • A: Acidosis (usually severe metabolic)
Renal Replacement Therapy ... renal replacement therapy ... Provides diffusive ... clearance by running ... #Replacement #Therapy
Treatment algorithm for VTE in Malignancy

(A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
anticoagulant therapy ... bleeding risk during ... DOAC, direct oral ... #DOAC #VTE #Malignancy
Hashitoxicosis

‘Leakage’ symptoms of active Hashimoto’s disease

- Hashitoxicosis (Htx) can occur during the initial hyperthyroid stage in
Htx) can occur during ... Diffuse infiltration ... Endocrinology #Diagnosis #Pathophysiology
Renal Replacement Therapy (RRT) Modalities

RRT Modalities in the ICU:
 • IHD (Intermittent HD):  3-5 hr
Renal Replacement Therapy ... renal replacement therapy ... Provides diffusive ... clearance by running ... #Replacement #Therapy
Intracranial Hemorrhage (ICH) and Increased Intracranial Pressure (ICP) - Pathophysiology
ICH Management:
1. Manage Blood Pressure
  •
Pressure (ICP) - Pathophysiology ... sedation • During ... Coagulopathy • DOACs ... Pressure #ICP #Pathophysiology
Peripartum Cardiomyopathy - Summary
1. Definition
 • Towards the end of pregnancy to 5 months postpartum
Management during ... Avoid Warfarin and DOAC ... Management during ... deteriorating on medical therapy ... investigative therapy
Magnesium Deficiency and Alcoholism

Risks associated with Mg deficiency in alcoholism:
 • Affects protein synthesis. energy production,
alcoholics, especially during ... normalized with Mg therapy ... Alcoholism #alcohol #pathophysiology