51 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... pylori test (GI symptoms ... test, ANA (e.g., SLE ... (CVID, WAS), (neurologic ... #Diagnosis #Causes
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Constitutional symptoms ... constitutional symptoms ... comparison #table #rheumatology ... #diagnosis #management
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
) - Diagnosis and ... 40, F:M 9:1 • Clinical ... Positive in 60-80% of cases ... Erythematosus #Diagnosis ... #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
) Clinical Manifestations ... autoantibodies that will cause ... #CNS #neurology ... #rheumatology # ... #management #treatment
Lupus Nephritis Primer
Class I - Minimal Mesangial
Class II - Mesangial Proliferative
Class Ill - Focal Proliferative
Class IV
Lupus #Nephritis #SLE ... Classification #Classes ... #differential # ... diagnosis #management ... #nephrology
Generalized Weakness - Differential Diagnosis Framework
"l feel weak":
 • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis
 •
Diagnosis Framework ... Rhabdomyolysis, Critical ... body-), PMR, RA, SLE ... #Diagnosis #causes ... #neurology
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
the face (many differential ... diagnoses, including ... including in children (pediatric ... #sle #clues #system ... erythematosus #rheumatology
Dizziness and Vertigo Algorithm
Presyncope:
 • Feels "faint" or like they are going to "pass out"
 •
"pass out" • Symptoms ... Associated with nausea ... Algorithm #dizzy #differential ... #diagnosis #neurology ... #management
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
Scl70 (in some cases ... Scl-70 (in some cases ... body-like: - Neurologic ... Cytoplasmic #Patterns #differential ... #diagnosis #rheumatology
Diplopia - Double Vision - Differential Diagnosis Algorithm
Clinical Pearls:
 • Diplopia is almost always binocular.
 •
Double Vision - Differential ... Clinical Pearls ... • Neurologic ... symptoms suggest ... #DoubleVision #Differential