379 results
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
• Increased thrombin ... protein C and S Pathophysiology ... organ damage Clinical ... significant fibrin clot
Pericardial Clot on Echocardiogram

ST elevation of acute pericarditis was misdiagnosed as STEMI and thrombolysed with SK
Pericardial Clot ... effusion with large clot ... Pericardial #effusion #clot ... #thrombus #Echocardiogram ... #POCUS #clinical
CLOT IN TRANSIT

IVC/RA View. "Peek-a-Boo phenomenon" (w/respiratory variation).

- Sam Ghali
@EM_RESUS

#Clinical #POCUS #IVC #Clots #Thrombus #InTransit
CLOT IN TRANSIT ... @EM_RESUS #Clinical ... #POCUS #IVC #Clots ... #Thrombus #InTransit
Mechanisms Driving Increased Thrombosis and Bleeding in Liver Disease
Increased Thrombosis 
Increased Platelet-Vesset Wall Interaction 
 •
ADAMTS 13 High Thrombin ... Thrombosis #Bleeding #Clot ... #Cirrhosis #Pathophysiology
Mesenteric Ischemia - Differential Diagnostic Schema
Chronic: ASCVD, Venous, Vasculitides 5% (PAN, [E]GPA, IgA, MPA)
Acute
 - Venous
least common): Thrombus ... Arterial - Thrombus ... inflammation → clot
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
FVa to generate thrombin ... Thrombin, then primes ... large amounts of thrombin ... #clot #PT #PTT ... models #hematology #pathophysiology
Left Main Coronary Artery Thrombus seen on Angiography

“Mother of all coronary thrombi”.  55 year old
Coronary Artery Thrombus ... of all coronary thrombi ... Thrombus protruding ... Coronary #Artery #Thrombus ... Angiogram #CathLab #clinical
Thromboelastogram Interpretation
Reaction Time (R Value):
 - Time till initiation of fibrin clot
 - Treatment: FFP, protamine
K
initiation of fibrin clot ... achieve 20 mm clot ... assay representing thrombin-platelet ... Maximum strength of clot ... Degradation of clot
Cool echo - RV strain, McConnell sign, and CLOT IN TRANSIT!! BP is normal and pt
McConnell sign, and CLOT ... @eabramsMD #Clinical ... Pulmonary #Embolism #Thrombus ... #Clots #InTransit
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC)
Platelet count:
 • Expected: Low (or normal)
 • Elevation
• Elevation in thrombin ... the presence of thrombin ... can accelerate thrombin ... broken down by thrombin ... to form clots,