18 results
Tumor Lysis Syndrome - Workup and Management

Initial workup: BMP, Serum uric acid, LDH, Urine output, Consider
Tumor Lysis Syndrome ... - Workup and Management ... of the above Treatment ... abnormalities • Cardiac ... #management #oncology
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
Classification of Tumor Lysis ... Syndrome (TLS) ... age and sex) • Cardiac ... TLS #diagnosis #management ... #oncology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
organ damage • Treatment ... lethargy, hematuria, cardiac ... Low calcium • Treatment ... with tetany or cardiac ... #diagnosis #management
Hypermagnesemia - Etiologies by Mechanism
Renal Failure 
Excessive Mg Administration 
 - Massive PO intake
Mechanisms - Tumor lysis ... syndrome Dr. ... Hypermagnesemia #Differential ... High #Magnesium #Table ... #Causes #Management
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
malignancies Treatment ... Interleukin-2) • Tumor lysis ... syndrome • Proximal ... #AKI #Cancer #Oncology ... #Differential #
Tumor Lysis Syndrome
An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... malignancies Treatments ... wandering_er #Tumor #Lysis ... #Syndrome #TLS ... #oncology #management
Shock - Differential Diagnosis Framework
 - MAP <65. SBP <90, drop in SBP > 40
 -
Shock - Differential ... Pneumothorax, Cardiac ... Abdominal compartment syndrome ... Dehydration Shock Treatment ... #management
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Rhabdomyolysis - Differential ... Diagnosis and Management ... iniury, Compartment syndrome ... per day until stable ... #Diagnosis #Management
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Diagnosis and Management ... Acidosis, Cell Lysis ... acidosis), CK+LDH (lysis ... Elimination (see Table ... line, stabilizes cardiac
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... initiation • Differential ... APML #diagnosis #management ... #hematology #oncology