672 results
Type III Hypersensitivity: Pathogenesis and clinical findings
Definition: Small antigen-antibody complexes (produced from normal immune response to
antigen-antibody complexes ... self-antigens are the cause ... antigens are the cause ... Allergy #Immunology #pathophysiology
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Manifestations • Immune Complex ... Myopathy (Also caused ... Complications #pathophysiology
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... immunofluorescence Immune Complex
Causes of B12 deficiency. 

This great diagram shows normal absorption and outlines most possible causes. At
Causes of B12 deficiency ... most possible causes ... The IF-Cbl complex ... #Differential #Causes ... #Diagnosis #Pathophysiology
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
Diagnosis Algorithm Cause ... intoxication Cause ... homeostasis is complex ... ⁻ increase may cause ... Diagnosis #Algorithm #Pathophysiology
Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings

Medical Comorbidities Malignancies (most commonly hairy-cell leukemia)
Immunogenetic Predisposition: patient is
antigen-antibody complexes ... Viral replication causes ... PolyarteritisNodosa #Pathophysiology
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
hair follicles -> causes ... inflammation (complex ... Manifestations #pathophysiology
Review of the Coagulation Cascade
Traditional Model:
 • Parallel extrinsic and intrinsic pathways.
Contemporary Model:
 • 4 key
multicomponent complexes ... Initiation phase caused ... models #hematology #pathophysiology
Approach to ECGs - VT vs. SVT - Wide Tachycardias
DDx = VT vs. SVT with BBB
All
VT: - No RS complexes ... - Very broad complexes ... produce a hybrid complex ... onset of the QRS complex ... S-wave - RSR' complexes
Mechanical Bowel Obstruction and Ileus - Pathogenesis and Clinical Findings
Ileus: Functional bowel "blockage", no peristalsis
Mechanical Obstruction:
of bowel lumen Complete ... bowel-movements (suggests complete ... light-switch pain") with complete ... percussion • Nausea ... obstruction #sbo #ileus #pathophysiology