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diagnosis diabetes endocrinology differential summary inhibitors management ophthalmology pupillary pupils agonists anisocoria anthracycline cardiology cardiotoxicity chemotherapy ckd dpp4 glp1 her2
Metformin Pharmacology Summary Mechanisms of Action: • Suppresses gluconeogenesis by the liver • Increases insulin-mediated glucose utilization
Metformin Pharmacology ... agent • Does not cause ... e.g. diarrhea, nausea ... #Metformin #Pharmacology ... #Summary #DM2 #
Isocoria - Pupillary Defects - Differential Diagnosis Algorithm Relative Afferent Pupil Defect • Optic Neuritis • Ischemic
Differential Diagnosis Algorithm ... dissociation) • Pharmacologic ... • Botulism Pharmacologic ... Differential #Diagnosis #Algorithm ... #Causes #Ophthalmology
GLP-1 Receptor Agonists - Pharmacology Summary Mechanisms of Action: Stimulate glucose-dependent insulin release from the pancreas (GLP-1
Receptor Agonists - Pharmacology ... e.g. diarrhea, nausea ... not definitively cause ... Receptor #Agonists #Pharmacology ... #Summary #DM2 #
Causes of Hypomagnesemia - Differential Diagnosis Algorithm GI LOSS - FeMg < 2-2.5% or 24h Urine Mg
Causes of Hypomagnesemia ... Differential Diagnosis Algorithm ... ab • Genetics defects ... -1beta, cyclin M2 ... Magnesium #Low #Causes
Anisocoria - Pupillary Defects - Differential Diagnosis Algorithm Physiological - Simple Anisocoria ( <O.5mm) - Anisocoria equal
Anisocoria - Pupillary Defects ... Differential Diagnosis Algorithm ... pilocarpine • Pharmacologic ... Pupillary #Pupils #Defects ... #Causes #Ophthalmology
SGLT2 Inhibitors SGLT2 inhibitors are the newest class of anti-diabetic medications, with the first one (Canagliflozin)
kidney), which causes ... drugs include side effects ... Side effects include ... SGLT2 #Inhibitors #Pharmacology ... #Medications #DM2
DPP-4 Inhibitors - Pharmacology Summary Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
4 Inhibitors - Pharmacology ... failure Common Side Effects ... not definitively cause ... DPP4 #Inhibitors #Pharmacology ... #Summary #DM2 #
Algorithm for Diagnosis and Management of Resistant Hypertension in CKD Pseudoresistant Hypertension - Reduce barriers to adherence:
Algorithm for Diagnosis ... Assess for adverse effects ... Consider other causes ... 30 mL/min/1.73 m2 ... Hypertension #CKD #Algorithm
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
slightly > Males • Affects ... hearing loss, nausea ... connective tissue components ... diseases 30% of cases ... ○ Syphilis ○ Fungal
Management of Anthracyclines and HER2 Antagonist Cardiotoxicity Anthracyclines cause cardiomyopathy: ✖ Reduction in left ventricular ejection fraction
Anthracyclines cause ... , 350 mg/m2, and ... HER2 agents cause ... monitoring to detect ... cardiology #oncology #pharmacology
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