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diagnosis differential hematology neurology cardiology causes infectiousdiseases algorithm anemia chronic erythematosus fungal gravis hemeonc hemolytic lupus myasthenia sle syndromes systemic
Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Lymphoproliferative disorders (e.g ... Myeloproliferative disorders (e.g ... thrombocythemia), Autoimmune ... disease • vWF ... #treatment #hematology
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
common in SLE, autoimmune ... microsomal) - Autoimmune ... - Vasculitis, e.g ... - Vasculitis, e.g ... diagnosis #table #rheumatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
(usually IgG) (e.g ... (usually IgM) (e.g ... deficiencies (e.g ... Hemoglobinopathies (e.g ... Membrane defects (e.g
Causes of Fever of Unknown Origin (FUO) - Differential Diagnosis • Infection: Extrapulmonary tuberculosis, Abscess, Endocarditis,
tuberculosis, Abscess, Endocarditis ... Infected thrombosis, (e.g ... Lemierre's syndrome ... (e.g. autoimmune ... , Kikuchi disease
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
mild to severe, Colour ... (e.g. oculomotor ... (AQP4-lgG disease ... ; e.g. narcolepsy ... Myositis, Comorbid autoimmune
Polyarteritis Nodosa (PAN) - Vasculitis Management Algorithm - ACR/VF 2021 Guidelines • Severe Disease → Remission
) - Vasculitis Management ... • Non-Severe Disease ... immunosuppressive agent (e.g ... #Treatment #ACR2021 ... Guidelines #algorithm #rheumatology
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Infectious • Endocarditis ... Hepatitis • HIV Autoimmune ... Obstructive Pulmonary Disease ... • Drug Abuse (e.g ... Chronic Fatigue Syndrome
Autoimmune Hemolytic Anemia (AIHA) Treatment Warm AIHA: 1) Steroids - 1-2 mg/kg prednisone daily • Until
Autoimmune Hemolytic ... Anemia (AIHA) Treatment ... Steroids - 1-2 mg/kg ... esp if severe disease ... #management #hematology
Endocarditis Summary Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV substance use • IV catheter • Recent
regurgitation • Autoimmune ... 90% of IE cases Culture ... staphylococci Culture ... ↑ ESR, CRP • EKG ... #diagnosis #management
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Subacute bacterial endocarditis ... GI - Felty syndrome ... , Vasculitis (e.g ... fever - Bacterial endocarditis ... differential #diagnosis #rheumatology
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