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signs symptoms management differential neurology treatment vasculitis hematology sle syndrome classification dermatology endocrinology erythematosus ophthalmology summary systemic algorithm comparison dermatomyositis
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Cerebrovascular Disease ... , PRES Pathophysiology ... autoantibodies that will cause ... CNS #neurology #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... valve lesions Abdominal ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... usually IgG) (e.g. lupus ... , Copper and lead ... #hematology #anemia
Functional Dyspepsia - Signs, Symptoms and Pathophysiology Delayed gastric emptying - Postprandial fullness, nausea, vomiting Hypersensitivity to gastric
Functional Dyspepsia - Signs ... postprandial fullness, abdominal ... nonerosive reflux disease ... gastroenterology #symptoms #diagnosis ... #signs
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... Post-strep GN, Lupus ... #differential #diagnosis ... #algorithm #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... 40, F:M 9:1 • Clinical ... Positive in 60-80% of cases ... Evolution: Chronic disease ... Management #Summary #rheumatology
Cullen's sign. Lipase 1,781. Bruising in the skin around the umbilicus. This sign is named after
conditions that cause ... Pathophysiology: ... pregnancy, or other causes ... Clinical Significance ... is not diagnostic
Cold Urticaria Prevalence - 0.05% in the population Disease onset - Mostly 2nd to 4th decades of life Causes
decades of life Causes ... and clinical associations ... , abdominal pain ... Cold #Urticaria #diagnosis ... #rheumatology #
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Discontinuation of causal ... Evolution: Chronic disease ... comparison #table #rheumatology ... #diagnosis #management
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings • Primary Sjögren's is a solitary process whereas secondary Sjögren's
Pathogenesis and Clinical ... other autoimmune diseases ... RA) or systemic lupus ... Sjogrens #Syndrome #Pathophysiology ... #Diagnosis #Signs
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