16 results
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Elevated Platelet Count ... Differential Diagnosis Algorithm ... workup, including BM ... Rebound effect from treatment ... Glucocorticoids, IL-1B, ATRA
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Injury - AKI Workup Algorithm ... Investigations: full blood count ... investigations depending on clinical ... ANCA, ANA, Anti-GBM ... #AKI #Workup #Algorithm
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
Infection in HIV / AIDS ... when the CD4-cell count ... should be based on clinical ... Antimicrobial treatment ... recovery (CD4-cell count
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... triad: Fever, Arthralgia ... Coxsackie, CMV, EBV ... diagnosis #management #treatment ... #rheumatology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Summary Acute AIDP ... - HIV, CMV, EBV ... meningococcal, H1N1) Clinical ... Guillain-Barre Clinical ... #neurology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
may precede the neurologic ... white blood cell count ... epilepticus Treatment ... underlying cause • Treatment ... Seizures: Treat with AEDs
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
Encephalopathy Triad ... : The clinical ... and with low CD4 counts ... disorder #dementia #AIDS ... #Neurology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Toxic injury to BM ... Aplastic Anemia Clinical ... aplastic anemia Treatment ... from low blood counts ... Anemia #oncology #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
organ damage Clinical ... : • Platelet count ... + Bleeding Treatment ... diagnosis #causes #treatment ... #management #hematology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
of HIV/AIDS patients ... be present: • AIDS ... noncompliance • Clinical ... initiation Clinical ... therapy (COAT TRIAL