13 results
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Elevated Platelet Count ... workup, including BM ... Rebound effect from treatment ... Vasculitides, IBD, Celiac disease ... Glucocorticoids, IL-1B, ATRA
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's Disease ... Clinical triad ... Coxsackie, CMV, EBV ... diagnosis #management #treatment ... #rheumatology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
Infection in HIV / AIDS ... when the CD4-cell count ... should be based on clinical ... Antimicrobial treatment ... Demyelinating disease
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... skin injury) • Neurologic ... : Arterial (MCC-small ... Behcet syndrome (Clinical ... Arthritis, AS Treatment
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
may precede the neurologic ... Shock, Autoimmune disease ... white blood cell count ... epilepticus Treatment ... underlying cause • Treatment
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
organ damage Clinical ... : • Platelet count ... • Severe Liver Disease ... + Bleeding Treatment ... #management #hematology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
of HIV/AIDS patients ... worsening of that disease ... be present: • AIDS ... noncompliance • Clinical ... initiation Clinical
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
Encephalopathy Triad ... : The clinical ... and with low CD4 counts ... disorder #dementia #AIDS ... #Neurology
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
has five major clinical ... extrapulmonary disease ... fungal stain of clinical ... yeast • At risk: AIDS ... Increased leukocyte count
Hepatorenal Syndrome (HRS)

Definition:
• Functional, potentially reversible kidney impairment.
• Occurs in advanced liver disease: cirrhosis, severe alcoholic
advanced liver disease ... • ↓ Effective arterial ... Diagnosis (Clinical ... Treatment Overview ... #Nephrology #Diagnosis