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differential algorithm hematology anemia nutrition thrombocytosis alopecia basophilia basophils cardiology celiac chf chronic copper diarrhea disease erythematosus fat fe gastroenterology
Causes of Iron Deficiency • Inadequate Intake: Vegetarian/vegan diet, Malnutrition • Increased Body Needs: Infants/preschoolers, Pregnancy,
Causes of Iron Deficiency ... Celiac disease • Inflammatory ... Disease (IBD, cancer ... ) #Iron #Deficiency ... #differential #diagnosis
Iron Deficiency in Heart Failure Pathophysiology: Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
Iron Deficiency ... an increase in inflammatory ... → Inflammation causes ... release Diagnosis ... #management #cardiology
Causes of Iron Deficiency • Diet: ↓ Intake, e.g. vegan, Malnutrition, Polyphenol / tannins, ↓ Vitamin
Causes of Iron Deficiency ... Diet: ↓ Intake, e.g ... Inflammation: IBD ... #Deficiency #Causes ... #differential #diagnosis
Gastrointestinal Causes of Iron Deficiency Anemia • Mass lesions: Carcinoma, Large polyps • Inflammatory: Reflux esophagitis,
Gastrointestinal Causes ... of Iron Deficiency ... Large polyps • Inflammatory ... Idiopathic ulcers, Crohn's ... #diagnosis
Causes of Iron Deficiency - Differential Diagnosis Algorithm • Blood loss: GI (cancer, ulcer, IBD), GU
Causes of Iron Deficiency ... - Differential Diagnosis ... cancer, ulcer, IBD ... other chronic inflammatory ... #Diagnosis #Causes
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... Acute or Chronic Inflammatory ... : • IBD • Rheumatic ... malignancy • Iron ... deficiency anemia
Causes of Copper Deficiency - Differential Diagnosis Hereditary: - Menkes disease, familial hypoceruloplasminemia Decreased / Inadequate Intake:
Causes of Copper ... conditions include inflammatory ... ulcerative colitis, Crohn's ... zinc ingestion (e.g ... supplementation) or iron
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... - Differential Diagnosis ... Volume (<80 fL) • Iron ... Chronic Disease (e.g ... #Anemia #MCV #Classification
Causes of Chronic Diarrhea - Differential Diagnosis Osmotic • Food/Drink: Lactose intolerance, Artificial sweeteners (e.g. sorbitol, high
Causes of Chronic ... - Differential Diagnosis ... Artificial sweeteners (e.g ... Ulcerative colitis, Crohn's ... classification
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... (specifically: iron ... deficiency, hemolysis ... hemorrhage) • Chronic inflammatory ... disorders (e.g.
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