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differential algorithm hematology nutrition anemia management alopecia b12 cardiology chf chronic classification cobalamin copper diarrhea elevatedmcv fat fe gastronintestinal heartfailure
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... - Differential Diagnosis ... Inflammatory: • IBD ... malignancy • Iron ... deficiency anemia
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... - Differential Diagnosis ... (specifically: iron ... deficiency, hemolysis ... inflammatory disorders (e.g
Causes of Iron Deficiency • Diet: ↓ Intake, e.g. vegan, Malnutrition, Polyphenol / tannins, ↓ Vitamin
Causes of Iron Deficiency ... Diet: ↓ Intake, e.g ... Inflammation: IBD ... #Deficiency #Causes ... #differential #diagnosis
Causes of Iron Deficiency - Differential Diagnosis Algorithm • Blood loss: GI (cancer, ulcer, IBD), GU
Causes of Iron Deficiency ... - Differential Diagnosis ... cancer, ulcer, IBD ... diet MALABSORPTION ... #Diagnosis #Causes
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased Heme Synthesis or
- Differential Diagnosis ... Deficiency (Eg ... Occult Bleed, Malabsorption ... , Dietary Deficiency ... #Differential #Diagnosis
Causes of Fat Malabsorption - Differential Diagnosis Biliary Duct Obstruction • Autoimmune— PBC, PSC • Infection— liver
Causes of Fat Malabsorption ... • Autoimmune— Crohn's ... Pancreatic lipase deficiency ... Celiac disease • IBD ... #Causes
Causes of Copper Deficiency - Differential Diagnosis Hereditary: - Menkes disease, familial hypoceruloplasminemia Decreased / Inadequate Intake:
Causes of Copper ... absorption: - Malabsorption ... ulcerative colitis, Crohn's ... zinc ingestion (e.g ... supplementation) or iron
Iron Deficiency in Heart Failure Pathophysiology: Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
Iron Deficiency ... → Inflammation causes ... release Diagnosis ... #deficiency #CHF ... #management #cardiology
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
B12 (Cobalamin) Deficiency ... • Common Causes ... diarrhea related to IBD ... consider other diagnosis ... #diagnosis #management
Causes of Chronic Diarrhea - Differential Diagnosis Osmotic • Food/Drink: Lactose intolerance, Artificial sweeteners (e.g. sorbitol, high
Causes of Chronic ... - Differential Diagnosis ... Artificial sweeteners (e.g ... ZE syndrome) Malabsorptive ... Ulcerative colitis, Crohn's
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