9 results
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
Hemophilia A - Deficiency ... celiac disease, CF, IBD ... ) • Anticoagulant ... table #comparison #diagnosis ... #hematology #deficiency
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
- Differential Diagnosis ... Ischemic Liver, IBD ... Vasculitis • Injury ... Venous #Arterial #pathophysiology ... #diagnosis #vascular
Iron Deficiency in Heart Failure
Pathophysiology:
Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
Iron Deficiency ... Heart Failure Pathophysiology ... and iron release Diagnosis ... #heartfailure #diagnosis ... #management #cardiology
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
at the site of injury ... clot #PT #PTT #diagnosis ... #models #hematology ... #pathophysiology ... anticoagulation #anticoagulant
Iron Deficiency in Congestive Heart Failure (CHF)

Iron deficiency (ID) in heart failure is a common comorbidity
Iron Deficiency ... (ID) in heart failure ... Exercise capacity Diagnosis ... #pharmacology #pathophysiology ... #cardiology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... Reduction of pro/anticoagulants ... thrombopoietin deficiency ... #Coagulation #diagnosis ... treatment #management #hematology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... Presentation: Injury ... bouts of HTN Diagnostic ... than 2/3 of the cross-sectional ... • Nutritional Deficiency
Review of the Coagulation Cascade
Traditional Model:
 • Parallel extrinsic and intrinsic pathways.
Contemporary Model:
 • 4 key
due to vascular injury ... fibrin, which is cross-linked ... Coagulation #Cascade #diagnosis ... #models #hematology ... #pathophysiology
Helpful Clinical Features in Evaluating Bleeding Disorders
Age of onset
 • Neonate - in 20% of haemophilias,
history, e.g. anticoagulants ... non-accidental injury ... or factor XIII deficiency ... peds #pediatrics #diagnosis ... #hematology #primarycare