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diagnosis hematology management causes oncology disorders infectiousdiseases thrombocytosis 1 abscess bandemia cbc cdi cdiff classification cll clostridioides clostridium difficile diffuse
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
Blood Disorders ... - Markers and Differential ... Diagnosis Algorithm ... , CD3 Chronic ... #Disorders #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Diagnosis Algorithm ... Artifact (redo CBC ... Myelofibrosis Infectious ... effect following treatment ... #Causes #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Diagnosis Algorithm ... hematologic: Acute blood ... Rebound effect from treatment ... Inflammatory Conditions: Rheumatologic ... : Chronic infections
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Diagnosis Algorithm ... Pseudotumor - Infectious ... Age > 50 • Chronic ... Lymphocytic Leukemia (CBC ... #Causes #Hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... →Activation of CD8 ... Phagocytosis of blood ... Unknown cause Treatment ... #summary #rheumatology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Disorders Testing Algorithm ... • Peripheral blood ... glucocorticoid treatment ... #Differential # ... diagnosis #hematology
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook Clinical Presentation + Progression:
Clostridioides Difficile Infection ... Diarrhea (>3 BM/d) ± blood ... Perforation) Pathophysiology ... Spore ingestion → colonic ... #1 nosocomial infection
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
of peripheral blood ... cultures, including blood ... #Bandemia #differential ... neutrophil #WBC #CBC ... #hematology #pathophysiology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... weeks without infection ... Lymphocytosis: Absolute blood ... microglobulin Treatment ... leukemia #CLL #Chronic
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
polymicrobial infection ... pneumonia • Chronic ... Lung Abscess Pathophysiology ... Diagnosis: • CBC ... anemia • Sputum/Blood
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