2206 results
Effect of Selected Diseases on Complement Levels - C3, C4
 • SLE C3 ↓ C4 ↓↓
, C4 • SLE C3 ... • MCGN type 1 C3 ... ↓ C4 ↓↓ • Cryo ... C3 ↓ C4 ↓↓ • ... #C4 #differential
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Significance (MGUS) - Differential ... immunotactoid GN, Type I cryo ... monoclonal Ig deposits, C3 ... Significance #MGUS #Differential
Glomerulonephritis - Differential Diagnosis Framework
ANCA:
 • C-ANCA: GPA (Wegener's)
 • P-ANCA: Microscopic Polyangiitis, Eosinophilic GPA (Churg
Glomerulonephritis - Differential ... Mediated: • ↓C3 ... Cryoglobulinemia • Normal C3 ... Glomerulonephritis #differential
Autoimmune Hemolytic Anemia (AIHA) Pathophysiology - Warm vs Cold AIHA
Warm AIHA:
 - 70%; IgG mediated
 -
IgG positive, C3 ... IgG negative, C3
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Pre-Renal:
 • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Injury (AKI) - Differential ... ANCA, Anti-GBM, C3 ... Kidney #Injury #Differential
Herpes Zoster C3 Distribution: Dermatomally distributed vesicles, many of which have coalesced, 
in patient with HZV
Herpes Zoster C3 ... HZV #Dermatomal #C3
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Cryoglobulinemia (85%), C3 ... Mnemonic #diagnosis #differential
Warm vs Cold Autoimmune Hemolytic Anemia
Warm Autoimmune Hemolytic Anemia:
 • Mechanism: IgG and Complement-mediated
 • Etiology:
positive for IgG +/- C3 ... Coombs Positive for C3
C3-C7 Fractures and Injuries - Which Fractures are Stable and Unstable

#Diagnosis #Orthopedics #C3C7 #Cervical #Fractures #Unstable
C3-C7 Fractures
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Algorithm and Differential ... blood count with differential ... , Anti-ds-DNA, C3 ... Workup #Algorithm #Differential