19 results
Effect of Selected Diseases on Complement Levels - C3, C4
 • SLE C3 ↓ C4 ↓↓
Selected Diseases on Complement ... • SLE C3 ↓ C4 ... ↓↓ • Cryo C3 ... • Infection eg SBE ... ThePeanutKidney #Complement
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Induced Lupus vs SLE ... • Immunologic Workup ... 90% - Low complement ... • Immunologic Workup ... 80% - Low complement
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE ... are evocative of SLE ... • Immunologic Workup ... 80% - Low complement ... management of SLE
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
anticoagulant • Complement ... Low C3 or low C4 ... Low C3 and low C4 ... Classification #Criteria #SLE
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus
Clinical and Immunologic Criteria

CLINICAL CRITERIA
 - ACUTE CUTANEOUS LUPUS
SLICC SLE Diagnostic ... anticoagulant - Low complement ... (C3, C4, or CH50 ... #Rheumatology #SLE
Causes of Approach to Altered Level of Consciousness - Workup
Clinical Exam - Focal
 • Trauma
 •
Consciousness - Workup ... Hemorrhage • See ... Refer to Blood Work ... #diagnosis #workup ... #algorithm #Causes
Bronchiectasis: diagnosis and management 

Causes of localized -> diffuse bronchiectasis
Foreign body, Bronchial stenosis (tumor, .. ),
RA, Sjögren, SLE ... #Differential #workup ... #algorithm #pulmonary
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Kidney Injury - AKI Workup ... Algorithm and Differential ... Anti-ds-DNA, C3/C4 ... #Injury #AKI #Workup ... #Algorithm #Differential
Hyperthyroidism (low TSH, High T4/T3) - Diagnostic Algorithm

Radioactive iodine scan – get if concern for nodular
) - Diagnostic Algorithm ... affects diagnostic workup ... management options (see ... Hyperthyroid #Diagnosis #Algorithm ... #Workup #Endocrinology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... anti-Smith Ab, low complements ... RNP antibodies, Complement ... levels (C3 and C4 ... activity • C3 C4