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differential algorithm management clinical causes cardiology pocus radiology table ultrasound signs comparison symptoms pathophysiology neurology classification peds hematology pediatrics nephrology
Cryoglobulinemia Classification Types Type 1: Monoclonal IgM (rarely IgG/lgA) • Raynaud phenomenon, Digital ulcers/gangrene, Livedo reticularis, Hyperviscosity
Cryoglobulinemia ... peripheral neuopathy, pulmonary ... MatthewHoMD #Cryoglobulinemia ... Types #hematology #diagnosis
Small Vessel Vasculitides • Granulomatosis with polyangiitis - Granulomatous manifestations (e.g., nasal crusting, destructive sinusitis, pulmonary
destructive sinusitis, pulmonary ... involvement • Cryoglobulinemic ... #differential #diagnosis
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
Pulmonary Renal ... Presentation (Pulmonary ... Differential Diagnosis ... Behcet disease, Cryoglobulinemia ... #differential #diagnosis
Pulmonary Renal Syndromes and Mimics - Differential Diagnosis Framework Diffuse alveolar hemorrhage + rapidly progressive glomerulonephritis 90%: -
Pulmonary Renal ... - Differential Diagnosis ... Complement Levels: SLE, Cryoglobulinemic ... Kumfer @AnnKumfer #Pulmonary ... #Differential #Diagnosis
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Lupus Nephritis, Cryoglobulinemia ... With associated pulmonary ... #differential #diagnosis
Hemoptysis - Differential Diagnosis Framework Massive Hemoptysis: >150-300 mL in 24h Airway disease: • Bronchitis, Bronchiectasis, Malignancy
- Differential Diagnosis ... > EGPA, MPA), Cryoglobulinemia ... #Differential #Diagnosis ... #pulmonary #causes
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
vasculitis, sepsis or cryoglobulinemia ... thrombophlebitis, pulmonary ... Cryofibrinogenemia Diagnosis ... Calciphylaxis • Cryoglobulinemia ... Cryofibrinogenemia #diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... progressing GN • New pulmonary ... ANCA +MPO) • Cryoglobulinemic ... Differential Diagnosis ... Low levels mixed cryoglobulinemia
Diagnosis of Cryoglobulinemia Vasculitis 1) Presence of cryoglobulin Circulating immunoglobulins that precipitate with cold temperature and dissolve
Diagnosis of Cryoglobulinemia ... ) MONOCLONAL CRYOGLOBULINEMIA ... TerrierBen #Cryoglobulinemia ... #Vasculitis #Diagnosis ... #Rheumatology #Cryoglobulinemic
Treatment of Non-hepatitis C virus Cryoglobulinemia Vasculitis - French Vasculitis Study Group MONOCLONAL CRYOGLOBULINEMIA (TYPE 1) IgM
Non-hepatitis C virus Cryoglobulinemia ... MONOCLONAL CRYOGLOBULINEMIA ... lenalinomide MIXED CRYOGLOBULINEMIA ... TerrierBen #NonHCV #Cryoglobulinemia ... Monoclonal #Mixed #Cryoglobulinemic
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