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differential management algorithm leukemia workup aplastic chronic cll hemeonc lymphocytic monoclonal myelodysplastic pancytopenia rheumatology acidosis activation cancer carcinoma causes classification
Aplastic Anemia Summary • Definition • Pathophysiology • DDx: AA vs Hypocellular MDS • Expectation •
Aplastic Anemia ... vs Hypocellular MDS ... #Aplastic #Anemia ... #diagnosis #oncology ... #hematololgy
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
(MD) - Diagnosis ... cytopenias (usually anemia ... #MDS #Diagnosis ... Management #treatment #hematology ... #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
(MDS) (normal or ... Hypocellular/Hypoplastic MDS ... abnormalities typical for MDS ... #oncology #hematology ... #diagnosis #management
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
- Differential Diagnosis ... Drug-associated, PCH, Evans Syndrome ... Defects: Sickle cell anemia ... Hypophostphatemia Laboratory ... #hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
and Differential Diagnosis ... HLH syndrome 5. ... Acquired Aplastic Anemia ... • Hypoplastic MDS ... #Algorithm #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... hemolysis, deficiency anemia ... Kawasaki, Nephrotic syndrome ... Matthew Ho, MD ... #Differential #Diagnosis
Tumor Lysis Syndrome - Workup and Management Initial workup: BMP, Serum uric acid, LDH, Urine output, Consider
Tumor Lysis Syndrome ... creatinine ratio Laboratory ... Matthew Ho, MD ... #diagnosis #management ... #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
(MDS) What? ... platelets) • MDS ... precursors MDS ... #diagnosis #hematology ... #oncology
Iron Deficiency Anemia - Differential Diagnosis Algorithm Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR • Blood loss:
Iron Deficiency Anemia ... - Differential Diagnosis ... Gastrectomy, WHDA syndrome ... Matthew Ho, MD ... Algorithm #ferritin #hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
and Differential Diagnosis ... HLH syndrome 5 ... Acquired Aplastic Anemia ... • Hypoplastic MDS ... #Algorithm #Hematology
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