18 results
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... Rare (SSA+ for cutaneous ... constitutional symptoms ... • Treatment: ... #sle #comparison
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... domain: Fever • Cutaneous ... , Acute cutaneous ... #EULARACR #Classification ... #Criteria #SLE
Lupus Classification
Spontaneous Lupus
 - Cutaneous Lupus Erythematosus (CLE)
 - Systemic Lupus Erythematosus 
Drug-Induced Lupus
 - Drug-Induced
Lupus Classification ... - Cutaneous Lupus ... Erythematosus (CLE ... (SCLE-DIL) - ... #Classification
Symptoms Distinguishing Groups of Cutaneous Drug Reactions
IgE-mediated reactions:
 • Onset minutes to hours into treatment course
Symptoms Distinguishing ... Groups of Cutaneous ... to hours into treatment ... dermatology #clinical #comparison ... #classification
Cutaneous Lupus Erythematosus
 • Acute Cutaneous Lupus (ACLE)
 • Neutrophilic Dermatoses 
 • Vascular Lesions
 •
Cutaneous Lupus ... Lupus (ACLE) ... Lupus (SCLE) ... Lupus (ICLE) ... #rheumatology #classification
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... involvement 3% SLE-Related ... , Cutaneous mimickers ... Lupusreference #SLE ... autoantibodies #signs #symptoms
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Skin Disease Classification ... : • Acute cutaneous ... scarring • Subacute cutaneous ... : • Symptoms limited
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... response -> Subacute cutaneous ... lupus: scaly annular ... #SLE #Mucocutaneous ... diagnosis #signs #symptoms
Management of Lupus Nephritis
Lupus nephritis (LN) in 10 to 40% of SLE
Hallmark = proteinuria 20.5 g/g
Nephritis Lupus ... in 10 to 40% of SLE ... severity (ISN/RPS classification ... by 12 months Classification ... Nephritis #Management #treatment
In order to better classify heart failure, the American College of Cardiology Foundation and the American
based solely on symptoms ... Below one can see ... With treatment, ... who never show symptoms ... past or current symptoms