15 results
Diagnosis of Cryoglobulinemia Vasculitis

1) Presence of cryoglobulin 
Circulating immunoglobulins that precipitate with cold temperature and dissolve
not related to clinical ... characterized into 3 types ... CRYOGLOBULINEMIA (type ... CRYOGLOBULINEMIA (types ... #Rheumatology #
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Syndrome, Mainly in Type ... Types: • Type ... arthritis) • Types ... • Type III Often ... #rheumatology #
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
bleeding disorder Clinical ... thrombocytopenia in type ... VonWillebrand #Disease #Diagnosis ... #Hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Autoimmune diseases • Clinical ... translocation • Types ... on: - Cell type ... Differential Diagnosis ... #differential #hematology
Suggested algorithm for bone marrow biopsy and skeletal imaging in patients with monoclonal gammopathy of undetermined
low-risk MGUS (IgG type ... whom there are no clinical ... Biopsy #algorithm #diagnosis ... #management #hematology
Von Willebrand Disease Classification
Type 1 (Accounts for ~3/4 of cases):
 • Defect: Quantitative defect (i.e. not
Classification Type ... : None-severe Type ... 2 (Type 2A, 2B, ... Moderate-severe Type ... #diagnosis #hematology
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Gammopathy of Clinical ... - Differential Diagnosis ... immunotactoid GN, Type ... #Differential #Diagnosis ... #hematology #oncology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Divided Into Two Types ... Cryofibrinogenemia Clinical ... : • + Clinical ... #rheumatology # ... hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Agglutinin Disease 3 Types ... Viral Infection Clinical ... Diagnosis: • hemolytic ... hemolytic #anemia #hematology ... #diagnosis
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause TYPE ... IV RTA, TYPE I ... salivary ducts Clinical ... nephritis • Distal (Type ... Sjogrens #Syndrome #Rheumatology