23 results
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table

Warm AIHA (48-70%)
Cold AHA (16-32%)
 • Donath-Landsteiner HA (paroxysmal
(AIHA) - Differential ... Diagnosis Table ... #AIHA #Differential ... #Diagnosis #Table ... #hematology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Diagnosis Framework ... Grafts, Valves, AS ... Drug-associated, PCH, Evans Syndrome ... Defects: Sickle cell anemia ... #Diagnosis #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... ) - HELLP syndrome ... Extravascular #Causes #differential ... #diagnosis #hematology ... #anemia
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 • Enzyme deficiencies ex. G6PD, pyruvate kinase 
 • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... Hypersplenism • AIHA ... HUS, DIC, HELLP, AS ... #Differential #
Differential diagnosis of schistocytes / fragmentation hemolysis:
 • Thrombotic microangiopathies (TMA)
    - TTP
Differential diagnosis ... formerly known as ... macroangiopathic hemolytic anemia ... " • HELLP syndrome ... #diagnosis #hematology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
et diutinum Neurologic ... • DADS-M • POEMS ... (-) hemolytic anemia ... #Monoclonal #Differential ... #Diagnosis #Oncology
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
- Markers and Differential ... Diagnosis Algorithm ... Lymphoid (ALL) - PAS ... Pelger-Huet, Macrocytic anemia ... #Diagnosis #Algorithm
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
women • 15% of AIHA ... Cold Agglutinin Syndrome ... anemia • Cold ... younger pts) Differential ... #hematology #diagnosis
Gerstmann Syndrome
1) Finger agnosia - Inability to name their own fingers, affecting both sides
2) Right-left confusion
Gerstmann Syndrome ... - Inability to differentiate ... Agraphia (without alexia ... patient is still able ... #neurology #diagnosis
Horner's Syndrome on Physical Exam

A 75yoF was referred in for facial swelling and eyelid changes 1
consistent with a diagnosis ... The video highlights ... #clinical #video ... ophthalmology #physicalexam ... #neurology #Anisocoria