59 results
TOPCAT - Spironolactone for Heart Failure with Preserved Ejection Fraction

N Engl J Med 2014; 370:1383-1392 https://www.nejm.org/doi/10.1056/NEJMoa1313731

CONCLUSIONS:
//www.nejm.org/doi ... ejection fraction, treatment ... cardiovascular causes ... , aborted cardiac ... dCHF #Cardiology #EBM
SALT-ED Trial - Balanced Crystalloids versus Saline in Noncritically Ill Adults

N Engl J Med 2018; 378:819-828
//www.nejm.org/doi ... hospital-free days between treatment ... crystalloids and treatment ... Crystalloids #Saline #AKI ... VisualAbstract #EBM
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
osmolarity If cause ... investigations depending on clinical ... ANCA, ANA, Anti-GBM ... CK-MB, NT-proBNP, cardiac ... Diagnosis #nephrology #causes
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
Syndrome (TLS) and Treatment ... Calcium ≤ 7.0 mg/dL Clinical ... TLS: • AKI (defined ... age and sex) • Cardiac ... hypocalcemia Treatment
Balanced Crystalloids vs. NormalSaline - My infographic about SALT-ED and SMART trial comparing crystalloids and saline
hospital-free days between treatment ... - Stage 2 AKI ... //www.nejm.org/doi ... Crystalloids #Saline #AKI ... VisualAbstract #LR #EBM
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... fever - ACS, AKI ... organ damage • Treatment ... lethargy, hematuria, cardiac ... with tetany or cardiac
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care

TRICC - NEJM 1999 -
Major Clinical Trials ... - NEJM 2018 - Cardiac ... unnecessary and cause ... ALI is the deadliest ... /vmoitra) #EBM
Cardiac Tamponade - Guidelines for Crises in Anaesthesia
Caused by an accumulation of blood, pus, effusion fluid
Cardiac Tamponade ... or iatrogenic causes ... • Call for cardiac ... thoracotomy is a better treatment ... anaesthesia #Cardiac
Syncope is a sudden, transient loss of consciousness, which is thought to be secondary to cerebral
be divided into cardiac ... frequently benign causes ... should be guided by clinical ... The treatment strategy ... depends on the cause
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
GrepMed Handbook Clinical ... Acute Diarrhea (>3 BM ... despite appropriate treatment ... Treatment Guideline ... diagnosis #management #treatment