29 results
TOPCAT - Spironolactone for Heart Failure with Preserved Ejection Fraction

N Engl J Med 2014; 370:1383-1392 https://www.nejm.org/doi/10.1056/NEJMoa1313731

CONCLUSIONS:
//www.nejm.org/doi ... ejection fraction, treatment ... cardiovascular causes ... , aborted cardiac ... dCHF #Cardiology #EBM
SALT-ED Trial - Balanced Crystalloids versus Saline in Noncritically Ill Adults

N Engl J Med 2018; 378:819-828
//www.nejm.org/doi ... hospital-free days between treatment ... crystalloids and treatment ... Crystalloids #Saline #AKI ... VisualAbstract #EBM
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
osmolarity If cause ... investigations depending on clinical ... ANCA, ANA, Anti-GBM ... CK-MB, NT-proBNP, cardiac ... Diagnosis #nephrology #causes
Balanced Crystalloids vs. NormalSaline - My infographic about SALT-ED and SMART trial comparing crystalloids and saline
hospital-free days between treatment ... - Stage 2 AKI ... //www.nejm.org/doi ... Crystalloids #Saline #AKI ... VisualAbstract #LR #EBM
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care

TRICC - NEJM 1999 -
Major Clinical Trials ... - NEJM 2018 - Cardiac ... unnecessary and cause ... ALI is the deadliest ... /vmoitra) #EBM
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... biologics (CMV +++, EBV ... Treatment: • ... diagnosis #management #treatment
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
GrepMed Handbook Clinical ... Acute Diarrhea (>3 BM ... despite appropriate treatment ... Treatment Guideline ... diagnosis #management #treatment
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
EGPA) • Renal: (AKI ... antibody, Anti-GBM ... (UPC) ratio • Cardiac ... Goodpasture's cause ... diagnosis #management #treatment
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... Coxsackie, CMV, EBV ... , DIC, TMA • Cardiac ... diagnosis #management #treatment
This is a quick overview of hormonal acne treatment for the medical student and resident.

Keep in
hormonal acne treatment ... #dermatology #treatment ... Trivedi M, Clark AK ... Koo EB, Petersen ... data review of 70 cases