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differential aflp hemolysis obstetrics pregnancy thrombocytopenia causes comparison ttphus algorithm common cvid extravascular fatty hemolytic hypogammaglobulinemia immunodeficiency immunology intravascular liver
Differential diagnosis of schistocytes / fragmentation hemolysis: • Thrombotic microangiopathies (TMA) - TTP
Differential diagnosis ... transplant • DIC ... macroangiopathic hemolytic anemia ... " • HELLP syndrome ... #hematology #hemolysis
Thrombocytopenia and Pregnancy Three syndromes in the critically ill pregnant woman who presents with coagulation defects. 1) HELLP
Pregnancy Three syndromes ... schistocytes, DIC ... AFLP #Obstetrics #OBGyn ... #Hematology #Diagnosis ... #Comparison #Table
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Megakaryopoiesis • Aplastic Anemia ... Non-lmmune: • HELLP ... Syndrome • TTP ... /HUS • DIC • ... Algorithm #Causes #Hematology
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP) Three syndromes in
Syndrome and Acute ... Pregnancy (AFLP) Three syndromes ... schistocytes, DIC ... AFLP #obstetrics #hematology ... #diagnosis #table
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
MAHA: TTP, HUS, DIC ... , HELLP - Grafts ... Drug-associated, PCH, Evans Syndrome ... Defects: Sickle cell anemia ... #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Microangiopathic hemolytic anemia ... ) - HELLP syndrome ... Hemolytic uremic syndrome ... #hematology #anemia
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
rapidly develops (DIC ... Preeclampsia, HELLP ... Liver #Pregnancy #hepatology ... #obstetrics #obgyn ... #diagnosis #management
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
autoimmune hemolytic anemia ... : • Nephrotic syndrome ... (Epstein-Barr syndrome ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
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